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The S. scabies 87-22 HBGC. (A) Schematic representation of the HBGC locus in S. scabies (http://strepdb.streptomyces.org.uk/). The horizontal line under the gene arrows marks the region replaced by the apramycin resistance gene, aac(3)IV in the Δhop615-1 and Δhop615-7 mutant strains. (B) Putative products of the S. scabies 87-22 HBGC: (i), hopene; (ii), aminotrihydroxybacteriohopane. Chemical structures are adapted from reference 29.
