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Domain architectures of KinA and truncated KinA mutants. The schematic diagram at the top shows an N-terminal sensor domain and a C-terminal autokinase domain. The sensor domain is further subdivided into three PAS domains (PAS-A, PAS-B, and PAS-C). The autokinase domain is further subdivided into a DHp and a CA domain (33, 47). The catalytic histidine (His405) is located within the DHp domain, as indicated. Amino acid residue numbers for domain boundaries are given above the diagrams.
