FIG. 7.

p30 sensitizes cells toward CD95-induced apoptosis. (A) Western blot analysis of expression levels of p30-210 or p30-216 in transfected BJAB cell lines with C15 MAb. In vitro-translated p30-210 and p30-216 were used as a positive control (*, unspecific band). (B) Analysis of the sensitivity of p30-overexpressing BJAB cells toward CD95-induced apoptosis after 16 h of treatment with the indicated concentrations of anti-APO-1 MAb. Vector-transfected BJAB cells were used as a negative control. (C) Analysis of the surface expression of CD95 in p30-overexpressing BJAB cells. (D) Analysis of the sensitivity of p30-overexpressing BJAB cells toward staurosporine- or UV-induced apoptosis after 16 h. Vector-transfected BJAB cells were used as a negative control.