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. 2008 Jan 3;22(4):858–867. doi: 10.1210/me.2007-0181

Table 1.

Fertility Test of TR4 Females

Genotype n Litters Pups Pups Per Litter Litters Per Female
TR4+/+ 5 20 179 8.95 ± 1.39 4 ± 0
TR4+/− 5 19 174 9.15 ± 1.34 3.8 ± 0.45
TR4−/− 5 12 63 5.25 ± 1.66b 2.4 ± 0.55a

Known fertile males were bred with 10- to 11-wk-old female littermates for 12 wk. Results are presented as mean ± sd

a

P < 0.05 vs. TR4+/+ and TR4+/−, Student's unpaired t test. 

b

P < 0.001 vs. TR4+/+ and TR4+/−, Student's unpaired t test.