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. 2009 Jul 6;83(4):626–635. doi: 10.1093/cvr/cvp192

Figure 5.

Figure 5

Inhibition of intimal hyperplasia in balloon-injured carotid arteries in rabbits by administration of NO-loaded ELIP and transcutaneous ultrasound. Representative histological sections of H&E-stained common carotid arteries in rabbits: (A) negative control (i.e. no balloon injury), (B) positive control (14 days after balloon injury of the artery), (C) sham (14 days after balloon injury of the artery plus pre-treatment with argon-loaded ELIP), and (D) treatment group (14 days after balloon injury of the artery plus pre-treatment with NO-loaded ELIP). NO ELIP significantly inhibited the development of intimal hyperplasia as a consequence of balloon injury to carotid arteries in rabbits. Published in J Am Coll Cardiol 2009, 54, Huang SL et al, Nitric oxide loaded echogenic liposomes for nitric oxide delivery and inhibition of intimal hyperplasia. Copyright Elsevier (2009).