Table 1. Borrelia hermsii isolates examined, history, origin, and IGS sequence types, western North America*.
| Isolate* | Year | Source | Locality | IGS type† |
|---|---|---|---|---|
| GGI | ||||
| HS1 | 1968 | Tick | Spokane Co., WA | 1 |
| CON | 1960s | Human | Sierra Nevada Mtns, CA | 1 |
| FRO | 1987 | Human | Eastern WA | 1 |
| DAH | 1991 | Human | Spokane Co., WA | 1 |
| FRE | 1996 | Human | Pend Oreille Co., WA | 1 |
| MIL | 1996 | Human | Kootenai Co., ID | 1 |
| BRO | 1996 | Human | Kootenai Co., ID | 1 |
| CAR | 1996 | Human | Benewah Co.,ID | 1 |
| BAK | 1997 | Human | Okanogan Co., WA | 1 |
| BYM | 1997 | Human | Kootenai Co., ID | 1 |
| RAL | 1997 | Human | Siskiyou Co., CA | 1 |
| SIS | 1998 | Ticks | Siskiyou Co., CA | 1 |
| HAL | 1998 | Human | Kootenai Co., ID | 1 |
| GAR | 2001 | Human | Okanagan Valley, BC | 1 |
| LAK-4 | 2004 | Human | Lake Co., MT | 1 |
| MAT | 2004 | Human | Bitterroot–Selway Mtns, ID | 1 |
| DOU | 2005 | Ticks‡ | Douglas Co., WA | 1 |
| EST-7 | 1996 | Chipmunk | Larimer Co., CO | 2 |
| ALL | 1997 | Human | Duchesne Co., UT | 2 |
| WAD | 1998 | Human | Placer Co., CA | 2 |
| SWA | 1996 | Human | Kootenai Co., ID | 5 |
| ELD | 2005 | Ticks‡ | Eldorado Co., CA | 6 |
| MAN | 1960s | Human | Sierra Nevada Mtns, CA | 7 |
| GGII | ||||
| YOR | 1964 | Human | Siskiyou Co., CA | 8 |
| REN | 1992 | Human | Okanogan Co., WA | 8 |
| OKA-1 | 1995 | Human | Okanagan Valley, BC | 8 |
| OKA-2 | 1996 | Human | Okanagan Valley, BC | 8 |
| OKA-3 | 1996 | Human | Okanagan Valley, BC | 8 |
| GMC | 1997 | Human | Stevens Co., WA | 8 |
| CMC | 1997 | Human | Stevens Co., WA | 8 |
| LAK-3 | 2004 | Human | Lake Co., MT | 8 |
| LAK-5 | 2004 | Human | Lake Co., MT | 8 |
| LAK-1 | 2002 | Human | Lake Co., MT | 9 |
| LAK-2 | 2002 | Human | Lake Co., MT | 9 |
| SIL | 2002 | Human | Boundary Co., ID | 9 |
| HAN | 1990 | Human | Boundary Co., ID | 9 |
| RUM | 1997 | Human | Stevens Co., WA | 10 |
*GGI, genomic group I; GGII, genomic group II; WA, Washington; Mtns, mountains; Co., county; ID, Idaho; CA, California, BC, British Columbia; MT, Montana; CO, Colorado; UT, Utah. †Each IGS sequence type is unique from the others and represented by the following isolate and GenBank accession nos.: type 1, DAH, DQ845746; type 2, ALL, DQ845747; type 5, SWA, DQ845746; type 6, ELD, DQ845745; type 7, MAN, DQ845748; type 8, YOR, DQ845744; type 9, LAK-1, DQ845742; type 10, RUM, DQ845743. Types 1 and 2 are identical to types of the same number in Bunikis et al. (AY515265 and AY515266, respectively) (6). No sequences matched types 3 and 4 identified by Bunikis and co-workers and are excluded here to avoid confusion. Types 5–10 are newly identified here. ‡DOU detected by PCR in a pool of 3 dead Ornithodoros hermsi. ELD based on spirochetes transmitted by O. hermsi to a laboratory mouse, followed by PCR of infected blood.