Table 3.

Side effects of PegIFNα-2α and rIFNα-2α (occurring in 35 % of the patients) and different doses of PegIFNα-2α alone (occurring in more than 15% of patients)⁹⁹,¹⁰⁸

Adverse effects	PegIFNα-2α μg (n = 559) (%)	rIFNα-2α 3 MIU (n =554) (%)	PegIFNα-2α 180 μg (n = 48) (%)	PegaIFNα-2α 360 μg (n = 53) (%)	PegIFNα-2α 450 μg (n = 49) (%)
Body as whole
Fatigue	56	57	52	57	59
Headache	54	58	19	26	35
Rigors	35	44	29	32	20
Fever	37	41	44	43	49
Central nervous system
Dizziness	16	12	6	9	20
Gastrointestinal
Nausea	24	33	42	34	39
Anorexia	17	17	21	21	41
Diarrhea	16	16	21	19	18
Musculoskeletal
Myalgia	37	38	19	19	29
Arthralgia	28	29	6	17	22
Musculoskeletal pain	9	10	12	17	20
Respiratory
Dyspnea	4	2	10	19	12
Coughing	4	3	19	8	20

Note: All values are %.