Table 1.
Sample | Age (years) | Gender (M/F) | PMI (hrs) |
Aβ Load (scale 0–8) |
||
AD | C | F | T | |||
1 | 74 | M | N/A | 2 | 8 | 8 |
2 | 72 | M | 18 | 0 | 8 | 8 |
3 | 87 | M | 4 | 0 | 4 | 6 |
4 | 83 | M | 5 | 0 | 8 | 8 |
5 | 84 | M | 2 | 1 | 4 | 4 |
6 | 88 | M | N/A | 0 | 8 | 8 |
7 | 72 | M | 2 | 3 | 8 | 8 |
8 | 79 | M | 23 | 0 | 8 | 8 |
9 | 92 | M | 10 | 0 | 6 | 6 |
10 | 82 | F | 4 | 2 | 8 | 8 |
11 | 83 | F | 2 | 2 | 7 | 7 |
12 | 85 | F | 3 | 0 | 7 | 5 |
Average | 81.7 +/- 6.3 | 7.3 | 0.8 | 7 | 7 | |
Controls | ||||||
1 | 67 | M | 3 | 0 | 0 | 0 |
2 | 74 | M | N/A | 0 | 2 | 0 |
3 | 87 | F | 24 | 0 | 3 | 3 |
4 | 62 | M | N/A | 0 | 0 | 0 |
5 | 89 | M | 6 | 0 | 0 | 0 |
6 | 85 | M | 48 | 0 | 4 | 3 |
7 | 87 | F | 4 | 0 | 0 | 0 |
8 | 78 | F | 6 | 0 | 4 | 3 |
9 | 87 | M | 12 | 0 | 2 | 0 |
Average | 79.5 +/- 9.9 | 14.7 | 0 | 1.7 | 1 |
Table summarizes the post mortem intervals (PMI) and the Aβ load for each brain tissue specimen used. The plaque counts were performed in specific areas using semi-quantitative measures generated using CERAD methodology. They are purely estimates of pathology on a scale of 0–8. There was no statistically significant difference in age between groups by T-test. In the AD group, the majority is males since the samples were obtained from a VA hospital.
C = Cerebellum; F = Frontal cortex; T = Temporal cortex; Gender: M = Male; F = Female; PMI = post mortem interval.