Table 1.

Patient demographics and clinical features overall and by treatment arm

Characteristic	Overalla (N=102)	Arm A (N=50)	Arm B (N=46)	P value (A vs. B)
Age (years)				0.2693
Median	9.03	8.77	9.19
Range	(0.05—21.00)	(0.31—21.00)	(0.05—20.24)
Race				0.3054
White	64	35	25
Black	19	7	10
Other	19	8	11
Sex				0.0706
Female	52	21	28
Male	50	29	18
Cytogenetics				0.0280
inv(16)	7	4	3
t(8;21)	11	6	5
t(9;11)	14	9	3
Other 11q23	12	7	5
Normal	18	2	13
Other	39	21	17
CNS status				0.1956
CNS1	69	33	31
CNS2	12	6	6
CNS3	3	2	0
Traumatic +	12	4	8
Traumatic -	1	0	1
FABb				0.5809
M0	3	3	0
M1	18	7	10
M2	22	9	12
M4	17	10	6
M4Eo	3	2	1
M5	18	8	9
M7	16	9	6
Other	5	2	2

^aSix patients declined to participate in the upfront therapy and were therefore not assigned to arm A or B.

^bFAB, French—American—British distribution