Table 4.
Feature | N | 5-yr OS ±SE (%) | p | 5-yr EFS ±SE (%) | p |
---|---|---|---|---|---|
| |||||
Sex | 0.274 | 0.321 | |||
Female | 52 | 55.8 ± 6.8 | 50.0 ± 6.8 | ||
Male | 50 | 44.0 ± 7.0 | 38.0 ± 6.9 | ||
| |||||
Race | 0.277 | 0.272 | |||
Black | 19 | 36.8 ± 10.4 | 31.6 ± 9.9 | ||
Other | 19 | 68.4 ± 10.3 | 63.2 ± 10.6 | ||
White | 64 | 48.4 ± 6.2 | 42.2 ± 6.2 | ||
| |||||
Cytogenetics | 0.811 | 0.528 | |||
inv(16) | 7 | 71.4 ± 15.6 | 71.4 ± 15.6 | ||
t(8;21) | 11 | 36.4 ± 13.0 | 36.4 ± 13.0 | ||
t(9;11) | 14 | 57.1 ± 12.5 | 57.1 ± 12.5 | ||
Other 11q23 | 12 | 50.0 ± 13.4 | 41.7 ± 13.0 | ||
Normal | 18 | 55.6 ± 11.7 | 33.3 ± 11.1 | ||
Other | 39 | 46.2 ± 7.8 | 43.6 ± 7.7 | ||
| |||||
CNS status | 0.367 | 0.338 | |||
CNS-negative | 69 | 51.7 ± 5.4 | 46.0 ± 5.3 | ||
CNS-positive | 12 | 40.0 ± 11.7 | 33.3 ± 11.1 | ||
| |||||
FAB | 0.882 | 0.837 | |||
M0/other | 7 | 57.1 ± 16.7 | 42.9 ± 16.2 | ||
M1 | 18 | 44.4 ± 11.7 | 38.9 ± 11.5 | ||
M2 | 22 | 45.5 ± 10.1 | 36.4 ± 9.7 | ||
M4/M4Eo | 20 | 45.0 ± 10.6 | 40.0 ±10.3 | ||
M5 | 18 | 66.7 ± 10.7 | 61.1 ± 11.0 | ||
M7 | 16 | 50.0 ± 11.8 | 50.0 ± 11.8 | ||
| |||||
MRD after window | 0.058 | 0.029 | |||
< 0.1% | 21 | 66.7 ± 10.3 | 66.7 ± 10.3 | ||
≥ 0.1% | 20 | 40.0 ± 10.3 | 35.0 ± 10.0 | ||
| |||||
MRD after DAV #1 | 0.024 | 0.003 | |||
< 0.1% | 27 | 63.0 ± 9.3 | 59.3 ± 9.5 | ||
≥ 0.1% | 17 | 35.3 ± 10.7 | 23.5 ± 9.2 | ||
| |||||
MRD after DAV #2 | 0.055 | 0.064 | |||
< 0.1% | 26 | 69.2 ± 9.1 | 65.4 ± 9.3 | ||
≥ 0.1% | 10 | 40.0 ± 13.9 | 40.0 ± 13.9 | ||
| |||||
Age >10 | 0.003 | 0.002 | |||
Yes | 47 | 34.0 ± 6.9 | 27.7 ± 6.5 | ||
No | 55 | 63.6 ± 6.4 | 58.2 ± 6.5 | ||
| |||||
Age (continuous) | 0.003 | 0.002 | |||
| |||||
Leukocyte count >50 | 0.316 | 0.228 | |||
Yes | 24 | 37.5 ± 9.4 | 33.3 ± 9.1 | ||
No | 78 | 53.8 ± 5.6 | 47.4 ± 5.7 | ||
| |||||
Leukocyte count (continuous) | 0.282 | 0.110 |