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. Author manuscript; available in PMC: 2010 Feb 1.
Published in final edited form as: Leukemia. 2009 Feb 26;23(8):1410–1416. doi: 10.1038/leu.2009.30

Table 4.

Analysis of prognostic factors

Feature N 5-yr OS ±SE (%) p 5-yr EFS ±SE (%) p

Sex 0.274 0.321
 Female 52 55.8 ± 6.8 50.0 ± 6.8
 Male 50 44.0 ± 7.0 38.0 ± 6.9

Race 0.277 0.272
 Black 19 36.8 ± 10.4 31.6 ± 9.9
 Other 19 68.4 ± 10.3 63.2 ± 10.6
 White 64 48.4 ± 6.2 42.2 ± 6.2

Cytogenetics 0.811 0.528
 inv(16) 7 71.4 ± 15.6 71.4 ± 15.6
 t(8;21) 11 36.4 ± 13.0 36.4 ± 13.0
 t(9;11) 14 57.1 ± 12.5 57.1 ± 12.5
 Other 11q23 12 50.0 ± 13.4 41.7 ± 13.0
 Normal 18 55.6 ± 11.7 33.3 ± 11.1
 Other 39 46.2 ± 7.8 43.6 ± 7.7

CNS status 0.367 0.338
 CNS-negative 69 51.7 ± 5.4 46.0 ± 5.3
 CNS-positive 12 40.0 ± 11.7 33.3 ± 11.1

FAB 0.882 0.837
 M0/other 7 57.1 ± 16.7 42.9 ± 16.2
 M1 18 44.4 ± 11.7 38.9 ± 11.5
 M2 22 45.5 ± 10.1 36.4 ± 9.7
 M4/M4Eo 20 45.0 ± 10.6 40.0 ±10.3
 M5 18 66.7 ± 10.7 61.1 ± 11.0
 M7 16 50.0 ± 11.8 50.0 ± 11.8

MRD after window 0.058 0.029
 < 0.1% 21 66.7 ± 10.3 66.7 ± 10.3
 ≥ 0.1% 20 40.0 ± 10.3 35.0 ± 10.0

MRD after DAV #1 0.024 0.003
 < 0.1% 27 63.0 ± 9.3 59.3 ± 9.5
 ≥ 0.1% 17 35.3 ± 10.7 23.5 ± 9.2

MRD after DAV #2 0.055 0.064
 < 0.1% 26 69.2 ± 9.1 65.4 ± 9.3
 ≥ 0.1% 10 40.0 ± 13.9 40.0 ± 13.9

Age >10 0.003 0.002
Yes 47 34.0 ± 6.9 27.7 ± 6.5
No 55 63.6 ± 6.4 58.2 ± 6.5

Age (continuous) 0.003 0.002

Leukocyte count >50 0.316 0.228
Yes 24 37.5 ± 9.4 33.3 ± 9.1
No 78 53.8 ± 5.6 47.4 ± 5.7

Leukocyte count (continuous) 0.282 0.110