Table 5.
Event-Free Survival | Overall Survival | |||||||
---|---|---|---|---|---|---|---|---|
Factor | HR | 95% CI | p | HR | 95% CI | p | ||
Favorable cytogenetics | 0.322 | 0.097 | 1.072 | 0.065 | 0.433 | 0.143 | 1.314 | 0.139 |
de novo AML | 0.013 | 0.001 | 0.120 | < 0.001 | 0.249 | 0.043 | 1.449 | 0.122 |
Leukocyte count | 1.014 | 1.005 | 1.023 | 0.004 | 1.002 | 0.992 | 1.011 | 0.744 |
Age | 1.114 | 1.008 | 1.231 | 0.034 | 1.115 | 1.015 | 1.225 | 0.023 |
MRD+ | 3.817 | 1.321 | 11.033 | 0.013 | 2.662 | 0.942 | 7.519 | 0.065 |
HR, hazard ratio
For favorable cytogenetics, de novo AML, and MRD, reported hazard ratios indicate rate of event or death among favorable cytogenetics relative to other patients, de novo patients relative to other patients, and MRD+ patients relative to MRD- patients. For leukocyte count, hazard ratio indicates relative change in event or death rate associated with an increase of 1,000 units in initial leukocyte count. For age, hazard ratio indicates relative change in event or death rate associated with a one-year increase in age.