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. 2008 May 23;30(4-2):507–518. doi: 10.1016/j.molcel.2008.03.011

Figure 3.

Figure 3

Binding Affinities between Histone Peptides and PHD or PHD-HD1

(A) ITC profiles for the binding of methylated and unmodified 15-mer histone H3 tail peptides to free hPHD, hPHD-HD1, or dPHD-HD1 complex, as indicated in the panels; data were fitted to a one-site model. Kd values are given in the individual panels (with fitting errors indicated; see the Supplemental Experimental Procedures).

(B) Binding constants (Kd values in μM) of free human and Drosophila PHD finger versus PHD-HD1 complex for various histone ligands, as indicated.

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