Figure 5.
Buttressing of the PHD A1 Cavity by HD1
(A) Molecular surface representation of PHD (green) with electrostatic potential, facing A1 cavity (left, yellow) and HD1 (right, orange).
(B) Buttressing of A1 cavity of PHD (molecular surface representation with electrostatic potential) by HD1 (ribbon representation). D352 lip residue of the K4me2 cavity and E360 residue critical for A1 anchoring are indicated.