Skip to main content
. 2009 Jun 10;111(1):27–36. doi: 10.1093/toxsci/kfp127

FIG. 5.

FIG. 5.

Average serum (upper panel) and brain (lower panel) concentrations of METH and AMP determined in dams and their litters on GD21. Pregnant rats were treated with 5.6 (left panel), 10 (middle panel), or 13.2 (right panel) mg/kg/day of METH via sc osmotic minipump from GD7 to GD21. Both dams and their litters were sacrificed on GD21 to determine serum and brain concentrations by LC-MS/MS. Serum and brain tissues were pooled for the entire litter from each dam for use in determining the METH and AMP concentrations. *p < 0.05 dam versus corresponding litter concentrations. All bars are shown as mean ± SD; n = 4–6 per data point.