Fig. 3.

CD36 rescues TR4-mediated reduced foam cell formation. (A) RAW-TR4siRNA cells were stably transfected with pCDNA3-flag-CD36 or empty vector. After selection with G418 (500 μg/mL) for 2 weeks, the cells were harvested and the CD36 protein expressions were confirmed by Western blot analysis. (B) Overexpression of CD36 rescues TR4-mediated reduced foam cell formation. The cells were seeded on a 96-well plate and exposed to 100 μg/mL oxLDL for 24 h. Oil red O staining was then performed. These data represent results from at least 2 independent experiments.