Table 1.
Descriptive characteristics of the CWRU/kentucky colon cancer genetic epidemiology study population
| Cases (n = 421 ) | Controls (n = 483) | P1 | |
| Age2 (yr) | 62.7 ± 10.6 | 57.6 ± 11.2 | < 0.0001 |
| Gender (%) | |||
| Female | 214 (50.8) | 307 (63.6) | 0.0001 |
| Male | 207 (49.2) | 176 (36.4) | |
| Race (%) | |||
| Caucasian | 394 (93.6) | 450 (93.2) | 0.3 |
| African-American | 22 (5.2) | 21 (4.4) | |
| Other | 5 (1.2) | 12 (2.5) | |
| BMI34 (kg/m2) | 29.2 ± 6.2 | 28.2 ± 6.0 | < 0.0001 |
| Family History35 | |||
| Yes | 94 (26.8) | 72 (17.1) | 0.0015 |
| No | 257 (73.2) | 349 (82.9) | |
| NSAID use36 (%) | |||
| Yes | 235 (64.2) | 306 (68.9) | 0.18 |
| No | 131 (35.8) | 138 (31.1) | |
| Physical activity3 (%) | |||
| Vigorous | 165 (42.7) | 247 (53.8) | 0.006 |
| Moderate | 106 (27.5) | 98 (21.4) | |
| Light | 115 (29.8) | 114 (24.8) |
1P-value of significance difference between cases and controls in a χ2 test (discrete variables and genotypes) or t-test (continuous);
2
Age (mean ± SD) at diagnosis for cases and age at recruitment for controls;
3
Calculations based on cases and controls with available information;
4
BMI (mean ± SD);
5
Family history of first-degree relatives with colorectal cancer;
6
NSAID: Yes = either ibuprofen or aspirin use in the last 6 mo.