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. 2009 Jun 10;3:7289. doi: 10.4076/1752-1947-3-7289

Figure 1.

Figure 1

Patient's clinical course. A: summary of therapy. B: serum creatinine. Insert: renal biopsy, haematoxylin and eosin stain (magnification ×200) and C1q immunoperoxidase stain (magnification ×400), showing diffuse active lupus nephritis class IV. Highlighting granular deposits in mesangium and capillary walls of all immunoglobulins and complements ("full house immunofluorescence"), distinguishing it from primary membranoproliferative glomerulonephritis. C: changes in autoantibodies pattern (Ho, homogenous; Sp, speckled) and D: complement C3 and C4 (lower limit of normal for C4 and ref range for C3 are shown). Changes in anti-DNA antibodies with time. Pred, prednisolone; MMF, mycophenolate mofetil.