Table 2.
Effect of co-infusion of PSL on the histopathological grade in 7 rabbits at 3 days after DXR infusion.
| Region | Loss of venous endothelial cells | p value | Inflammatory cell infiltration | p value | Edema | p value | Thrombus | p value | Epidermal degeneration | p value | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Grade | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | 0 | 1 | 2 | 3 | ||||||
| Proximal | with normal saline | 4 | 3 | 0 | 0 | N.S. | 0 | 3 | 4 | 0 | N.S. | 0 | 1 | 3 | 3 | <0.05 | 7 | 0 | 0 | 0 | N.S. | 7 | 0 | 0 | 0 | N.S. |
| with PSL | 6 | 1 | 0 | 0 | 0 | 5 | 1 | 1 | 0 | 4 | 3 | 0 | 7 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | ||||||
| Distal | with normal saline | 2 | 4 | 1 | 0 | N.S. | 0 | 3 | 4 | 0 | N.S. | 0 | 1 | 2 | 4 | N.S. | 7 | 0 | 0 | 0 | N.S. | 7 | 0 | 0 | 0 | N.S. |
| with PSL | 5 | 1 | 1 | 0 | 1 | 2 | 4 | 0 | 1 | 1 | 2 | 3 | 7 | 0 | 0 | 0 | 7 | 0 | 0 | 0 | ||||||
Numbers in the table represent the number of observations. P values indicate a significant difference between the normal saline and PSL groups. N.S.; not significant.