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Schematic depiction of the components of the airway allergic inflammatory response. PRR (pattern recognition receptor); PAR (protease activated receptor); TSLP (thymic Stromal Lymophopoietin); GM-CSF (granulocyte-macrophage colony stimulating factor). Arrows indicate the direction in which the identified signal is acting. Red lines indicate the discharge of cellular mediators (including granular contents, lipid mediators and cytokines).
