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. Author manuscript; available in PMC: 2010 Jun 5.
Published in final edited form as: Circ Res. 2009 May 7;104(11):1260–1266. doi: 10.1161/CIRCRESAHA.108.191718

Figure 3.

Figure 3

(A) Schematic representation of the Seryl-tRNA synthetase protein and the location of the lesions in the two mutant alleles Sarss277 and Sarss228. The blue bar outlines a highly homologous area containing the serine-recognition site, the red bar the conserved enzymatic core, and the green bar the vertebrate-specific C-terminal appendage.

(B-D) Cycloheximide (cyc) treatment of zebrafish embryos between 60 and 72hpf; epifluorescence micrographs of DMSO-control (B), 100μM cyc (C) and 200μM cyc (D) treated larvae visualized for Tg(flk1:EGFP)s843 expression.