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Treatment of wild type mice with Siglec-F antibody decreases numbers of circulating eosinophils. Wild type (Balb/c) mice were treated with indicated doses of the sheep polyclonal Siglec-F antibody and the quantum of eosinophils (panel A) and total leukocytes (panel B) in peripheral blood are shown. Representative data from one of three experiments (each performed with four mice/group) is shown. Data are mean ± SD. P-value is determined by two-tailed, equal variance t-test.
