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. 2009 Aug 28;5(8):e1000489. doi: 10.1371/journal.pcbi.1000489

Table 2. Summary of E-Flux predicted mycolic acid enhancers from Boshoff data set.

Predicted Enhancers
Chlorpromazine/GSNO Non-specific Weak* New
Rifapentine Non-specific Weak New
Rifampicin Non-specific Weak New
Chlofazimine/GSNO Non-specific Weak New
GSNO Specific Strong* New
Menadione/GSNO Non-specific Very weak* New
Triclosan Non-specific Very weak* Incorrect?

Results are shown for all significant predictions from the set of 437 experiments in Boshoff et al [17]. Strong effects are defined as effects showing greater than +/−3 log change between control and drug; weak enhancing effects have greater than +1 log change, and we list two very weak effects defined as prediction lying outside the 95% null confidence interval. Specific effects indicate effects on mycolic acid biosynthesis as contrasted to effects over a broad range of pathways – see text for more details.

*

Prediction made only for certain replicates.

Prediction made only for certain doses.

Conditions with both enhancing and inhibiting predictions among replicates were excluded.

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