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. Author manuscript; available in PMC: 2010 Jul 23.
Published in final edited form as: Cell. 2009 Jul 23;138(2):286–299. doi: 10.1016/j.cell.2009.05.045

Figure 3. Increased CD47 Expression in Human AML is Associated with Poor Clinical Outcomes.

Figure 3

Event-free (A,C) and overall (B,D) survival of 132 AML patients with normal cytogenetics (A,B) and the subset of 74 patients without the FLT3-ITD mutation (C,D). Patients were stratified into low CD47 and high CD47 expression groups based on an optimal threshold (28% high, 72% low) determined by microarray analysis from an independent training data set. The significance measures are based on log-likelihood estimates of the p-value, when treating the model with CD47 expression as a binary classification.