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. 2009 Aug 24;4(8):e6720. doi: 10.1371/journal.pone.0006720

Table 3. Differentially expressed proteins identified from Y. pestis at 37°C.

Protein number Protein name Accession No. Function Method Fold change
WT/ΔrelAΔspoT
1 LcrH (SycD) secretion chaperone YPCD1.30c chaperone for YopBD MALDI 2.3
2 FrsA (fermentation/respiration switch protein) y0964 FrsA may promote fermentation MALDI 2.8
3 MetK (S-adenosylmethionine synthetase) y3314 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase MALDI 4.2
4 CodA (cytosine deaminase) y3946 salvage of nucleosides and nucleotides MALDI 1.5
5 Pla (outer membrane protease) YPPCP1.07 outer membrane protease; involved in virulence in many organisms MALDI 2.6
6,7,8 LcrV (secreted effector protein) YPCD1.31c functions in needle complex protein export; Yop secretion and targeting control protein; important for translocation pore formation MALDI 7.3
9 TrpA (tryptophan synthase subunit alpha) y2047 amino acid biosynthesis: Tryptophan MALDI 1.6
10 TyrS (tyrosyl-tRNA synthetase) y1966 aminoacyl tRNA synthetases, tRNA modification MALDI 1.6
11 hypothetical protein y2786 putative membrane protein MALDI 2.3
12 Kbl (2-amino-3-ketobutyrate coenzyme A ligase) y0081 Central intermediary metabolism: pool, multipurpose conversions MALDI 1.7