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. 2000 Jan 22;320(7229):220–224. doi: 10.1136/bmj.320.7229.220

Table 3.

Diagnostic value of different methods to detect left ventricular systolic dysfunction where previous screening brought the unconditional probability of systolic dysfunction to 12%

Type of test Left ventricular systolic dysfunction
Predictive value
Specificity (%) Sensitivity (%) Negative likelihood ratio P value
Yes No Positive Negative
QRS or ST-T changes, or both, on electrocardiography:
 Yes 13 49 21 97 56 87 0.24 0.005
 No 2 62
Treated for congestive heart failure:
 Yes 9 34 21 93 69 60 0.58 0.050
 No 6 77
Confirmed myocardial infarction:
 Yes 7 24 23 92 78 47 0.68 0.073
 No 8 87
N-terminal atrial natriuretic peptide>0.8 nmol/l:
 Yes 6 12 33 92 89 43 0.62 0.006
 No 8 95
Heart rate>diastolic blood pressure:
 Yes 8 15 35 93 86 53 0.55 0.001
 No 7 95

Left ventricular systolic dysfunction is roughly equal to an ejection fraction⩽0.45. Minnesota codes for Q wave (1.1-1.3), left bundle branch block (7.1), ST-T abnormalities (4.1-4.4; 5.1-5.4; 9.2) and left ventricular hypertrophy (3.1; 3.3; 3.4) were used.9