Table 1.
Myocardial tissue lipid content
| Lean control | Obese ZDF | |
|---|---|---|
| Triacylglycerol (μmol FA (g wet wt)−1) | 4.3 ± 0.6 | 10.3 ± 1.4* |
| Total cholesterol (μmol (g wet wt)−1) | 9.8 ± 1.3 | 8.7 ± 2.2 |
| Phospholipid (μmol (g wet wt)−1) | 41.2 ± 6.8 | 49.5 ± 7.6 |
| Non-esterified fatty acid (μmol (g wet wt)−1) | 0.37 ± 0.07 | 0.61 ± 0.09 |
Results are expressed as means ±s.e.m. (n= 5 per group). FA, fatty acid. Animals were fed ad libitum, and following blood sampling the heart was removed, frozen in liquid N2 and ground to powder; lipids were extracted and analysed for lipid content. For further details see text. Statistically significant differences between obese ZDF rats and lean littermates are indicated: *P < 0.05.