Table 1.
Demographics and clinicopathological characteristics
| Parameters | Study group | Non-cirrhotics(n = 29) | Cirrhotics(n = 15) |
|---|---|---|---|
| Age (years) | |||
| Median | 62.4 | 62.1 | 62.3 |
| Range | 19.7–87.5 | 19.7–80.5 | 32.7–87.5 |
| Gender | |||
| Male | 33 | 20 (60.9%) | 13 (86.7%) |
| Female | 11 | 9 (31.0%) | 12 (13.3%) |
| Aetiology | |||
| Hepatitis B | 15 | 7 | 8 |
| Hepatitis C | 3 | – | 3 |
| Alcohol | 5 | 3 | 2 |
| Haemochromatosis | 5 | 3 | 2 |
| Unknown | 16 | 16 | – |
| Child–Pugh score | |||
| A | 35 | 24 | 11 |
| B | 7 | 3 | 4 |
| Unknown | 2 | 2 | – |
| Type of resection | |||
| Right hepatectomy | 13 | 6 | 7 |
| Left hepatectomy | 4 | 3 | 1 |
| Extended right hepatectomy | 7 | 6 | 1 |
| Extended left hepatectomy | 3 | 3 | – |
| Central resection | 3 | 2 | 1 |
| Left lateral resection | 4 | 3 | 1 |
| Segmentectomy | 10 | 6 | 4 |
| Serum αFP-level (ng/ml) | |||
| Median | 33.5 | 33.5 | 29.0 |
| Range | 0.2–168000 | 2.0–168000 | 2.0–168000 |
| Tumour size (cm) | |||
| Mean (SD) | 13.5 ± 3.2 | 13.2 ± 3.0 | 14.1 ± 3.7 |
| Median | 12.4 | 12.3 | 13 |
| Range | 10.0–20.0 | 10.0–20.0 | 10.0–20.0 |
| No. of lesions | |||
| Solitary | 23 | 17 (58.6%) | 6 (40%) |
| Multiple | 21 | 12 (41.4%) | 9 (60%) |
| Lobar involvement | |||
| Unilobar | 32 | 21 (72.4%) | 11 (73.3%) |
| Bilobar | 12 | 8 (27.6%) | 4 (26.7%) |
| Ruptured tumours | 6 | 5 (17.2%) | 1 (6.7%) |
| Portal vein thrombus | 5 | 1 (3.4%) | 4 (26.7%) |
| Microvascular invasion | 27 | 16 (48.3%) | 11 (73.3%) |
| Positive margins | 22 | 13 (44.8%) | 9 (60.0%) |
| Histology | |||
| Fibrolamellar | 8 | 7 | 1 |
| Well differentiated | 8 | 6 | 2 |
| Moderately differentiated | 21 | 10 | 11 |
| Poorly differentiated | 7 | 6 | 1 |