Table 2.
Variables | Frequency | Overall survival |
Disease-free survival |
||||||
---|---|---|---|---|---|---|---|---|---|
1-year (%) | 3-year (%) | 5-year (%) | P-value | 1-year (%) | 3-year (%) | 5-year (%) | P-value | ||
Gender | 0.345 | 0.418 | |||||||
Male | 33 | 62.1 | 35.1 | 21.1 | 46.7 | 22.3 | 14.9 | ||
Female | 11 | 81.8 | 46.8 | 46.8 | 60.0 | 30.0 | 30.0 | ||
Age | 0.176 | 0.075 | |||||||
<65 years | 25 | 70.4 | 49.4 | 38.4 | 56.7 | 36.0 | 36.0 | ||
>65 years | 19 | 61.5 | 23.5 | 11.7 | 40.9 | 9.1 | 0.0 | ||
Cirrhosis | 0.014 | 0.286 | |||||||
Yes | 15 | 44.0 | 12.2 | 0.0 | 50.0 | 15.0 | 0.0 | ||
No | 29 | 77.8 | 48.5 | 39.7 | 48.4 | 27.2 | 27.2 | ||
Child–Pugh score | 0.438 | 0.569 | |||||||
A | 35 | 70.2 | 37.5 | 28.5 | 50.9 | 26.3 | 19.7 | ||
B | 7 | 51.4 | 34.3 | 17.1 | 40.0 | 20.0 | 20.0 | ||
Serum αFP-level | 0.711 | 0.486 | |||||||
<400 ng/ml | 28 | 73.2 | 41.3 | 25.8 | 48.8 | 25.3 | 19.0 | ||
≥400 ng/ml | 12 | 58.3 | 24.3 | 24.3 | 43.6 | 14.5 | 14.5 | ||
No. of lesions | 0.490 | 0.570 | |||||||
1 | 23 | 76.0 | 31.3 | 31.3 | 51.7 | 26.2 | 26.2 | ||
>1 | 21 | 56.1 | 44.9 | 24.1 | 46.8 | 19.5 | 0.0 | ||
Lobar involvement | 0.670 | 0.658 | |||||||
Unilobar | 32 | 66.8 | 31.8 | 27.3 | 42.8 | 22.5 | 22.5 | ||
Bilobar | 12 | 64.8 | 54.0 | 28.8 | 66.7 | 26.7 | 13.3 | ||
Portal vein thrombus | 0.157 | 0.003 | |||||||
Yes | 5 | 20.0 | 20.0 | 20.0 | 0.0 | 0.0 | 0.0 | ||
No | 39 | 72.7 | 40.3 | 28.3 | 54.3 | 26.2 | 20.9 | ||
Rupture | 0.123 | 0.945 | |||||||
Yes | 6 | 66.7 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | ||
No | 38 | 66.8 | 41.7 | 30.4 | 51.8 | 24.9 | 19.9 | ||
Microvascular invasion | 0.032 | 0.038 | |||||||
Yes | 27 | 57.5 | 22.5 | 22.5 | 33.3 | 13.9 | 13.9 | ||
No | 17 | 80.7 | 64.5 | 38.7 | 71.8 | 36.5 | 24.3 | ||
Margin involvement | 0.565 | 0.744 | |||||||
Yes | 22 | 51.6 | 36.1 | 36.1 | 39.7 | 29.8 | 29.8 | ||
No | 22 | 81.1 | 41.6 | 22.3 | 58.7 | 19.6 | 13.0 | ||
Histology | <0.001 | 0.093 | |||||||
Fibrolamellar | 8 | 87.5 | 58.3 | 58.3 | 50.0 | 33.3 | 33.3 | ||
Well differentiated | 8 | 83.3 | 66.7 | 50.0 | 66.7 | 50.0 | 50.0 | ||
Moderately differentiated | 21 | 65.8 | 32.5 | 16.2 | 55.4 | 10.1 | 0.0 | ||
Poorly differentiated | 7 | 28.6 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | ||
Surgical modality | 0.161 | 0.775 | |||||||
Resection only | 28 | 77.0 | 41.1 | 35.9 | 49.9 | 23.3 | 23.3 | ||
Resection and ablation | 16 | 50.0 | 34.3 | 12.9 | 50.0 | 26.7 | 0.0 | ||
Ethnicity | <0.001 | 0.003 | |||||||
Asians | 13 | 38.5 | 7.7 | 0.0 | 11.4 | 0.0 | 0.0 | ||
Non-Asians | 31 | 79.3 | 53.5 | 42.5 | 64.2 | 33.4 | 26.7 |