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New Agents for MDS
| Class/Mechanism of Action | Agent (Trade) |
|---|---|
| DNA methyltransferase inhibitor | Azacitidine (Vidaza®) Decitabine (Dacogen™) |
| HDAC | Phenylbutyrate Valproic acid MS-275 MGCD0103 Vorinostat (Zolinza®) |
| Farnesyltransferase inhibitor | Tipifarnib Lonafarnib |
| TNF inhibitor | Etanercept (Enbrel®) |
| Suppression of the abnormal 5q31 clone | Lenalidomide (Revlimid®) |
| Retinoid | All-trans retinoic acid (ATRA) |
| Nucleoside analog | Sapacitabine |
| Glutathione analog | TLK199 |
