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. Author manuscript; available in PMC: 2010 May 1.
Published in final edited form as: J Neurochem. 2009 May;109(3):923–934. doi: 10.1111/j.1471-4159.2009.06021.x

FIGURE 5. Characterization of the TM1 aromatic residue P2XR mutants.

FIGURE 5

(A) Comparison of maximum current amplitudes stimulated by supramaximal ATP concentrations in cells expressing the WT and mutant P2X2aR, P2X3R, and P2X4R. (B–D) Dose-response curves for ATP (left) and αβ–;meATP (right) in cells expressing aromatic residue mutants of the P2X2a (B), P2X3R (C), and P2X4R (D). The αβ-meATP efficacy was measured by comparison with the maximum effect of ATP.