Table 7.
Quintile of Waist-Hip Ratio |
P trend | |||||||||
1 | 2 |
3 |
4 |
5 |
||||||
Referent | HR | 95% CI | HR | 95% CI | HR | 95% CI | HR | 95% CI | ||
Incident diabetes, 1987–1998 | ||||||||||
No. of participants | 2,042 | 2,057 | 2,043 | 2,022 | 2,015 | |||||
Events | 63 | 139 | 213 | 307 | 450 | |||||
Person-years | 16,504 | 16,227 | 15,769 | 15,268 | 14,176 | |||||
Waist-hip ratio | 1.00 | 2.21 | 1.64, 2.98 | 3.34 | 2.52, 4.43 | 4.87 | 3.70, 6.40 | 7.65 | 5.85, 10.00 | <0.0001 |
Incident coronary heart disease, 1987–2003 | ||||||||||
No. of participants | 2,145 | 2,169 | 2,156 | 2,142 | 2,155 | |||||
Events | 143 | 185 | 229 | 254 | 297 | |||||
Person-years | 30,874 | 31,026 | 30,505 | 30,129 | 29,631 | |||||
Waist-hip ratio | 1.00 | 1.22 | 98, 1.52 | 1.47 | 1.19, 1.81 | 1.54 | 1.25, 1.90 | 1.73 | 1.41, 2.13 | <0.0001 |
Abbreviations: CI, confidence interval; HR, hazard ratio.
Adjusted for age, race, sex, clinical center, level of education (≤high school graduate, >high school graduate), current smoking status at baseline (yes, no) and pack-years of cigarette smoking (quartiles), alcohol consumption (none vs. any), family history of diabetes (yes, no, unknown), baseline menopausal status (yes, no) and baseline hormone use by women (current yes, no), Keys’ score (quintiles), cereal fiber (grams per day in quintiles), fruit and vegetable intake (servings per day in quintiles), physical activity (score of ≥2 or < 2 on the Baecke sport index).