Table 3.

Odds Ratios and 95% Confidence Intervals for the Association Between a GSTP1 Exon 5 (Ile105Val, 313A → 313G) Polymorphism (Ile/Val and Val/Val vs. Ile/Ile) and Lung Cancer in the Pooled Analysis, Stratified by Smoking Status and Ethnicity

Ethnic Group	No. of Cases	No. of Controls	OR	95% CI
Asian
All studies: unadjusted	603	768	1.34	1.07, 1.67
All studies: adjusteda	603	768	1.35	1.07, 1.70
Hospital controls: unadjusted	599	758	1.32	1.06, 1.65
Hospital controls: adjusteda	599	758	1.32	1.05, 1.68
Smoker: unadjusted	287	298	1.23	0.88, 1.72
Smoker: adjustedb	287	298	1.17	0.83, 1.66
Smoker: adjustedc	48	49	1.06	0.41, 2.75
Nonsmoker: unadjusted	254	390	1.49	1.08, 2.07
Nonsmoker: adjustedb	254	390	1.52	1.09, 2.13
White
All studies: unadjusted	3,538	4,098	1.07	0.98, 1.17
All studies: adjusteda	3,490	4,077	1.05	0.95, 1.16
Healthy controls: unadjusted	1,503	2,268	1.12	0.98, 1.27
Healthy controls: adjusteda	1,497	2,254	1.15	0.99, 1.33
Hospital controls: unadjusted	2,035	1,830	1.02	0.90, 1.16
Hospital controls: adjusteda	1,993	1,823	1.00	0.87, 1.14
Smoker: unadjusted	3,044	2,737	1.02	0.93, 1.14
Smoker: adjustedb	3,035	2,729	1.05	0.95, 1.17
Smoker: adjustedc	2,809	2,181	1.00	0.89, 1.13
Nonsmoker: unadjusted	465	1,352	1.18	0.95, 1.45
Nonsmoker: adjustedb	455	1,348	1.17	0.92, 1.49

Abbreviations: CI, confidence interval; GSTP1, glutathione S-transferase pi gene; Ile, isoleucine; OR, odds ratio; Val, valine.

^aAdjusted for study ID (an assigned study identifier for each study population), age, sex, and smoking status (ever/never).

^bAdjusted for study ID, age, and sex.

^cAdjusted for study ID, age, sex, and pack-years of smoking.