Table 4.

Relations of Urinary Concentrations of Di-(2-Ethylhexyl) Phthalate Metabolites in Pregnant Women to Clinical Outcomes Related to Parturition and Labor in Logistic Regression Models (n = 283), Study for Future Families, 2000–2004^a

Outcome	No. of Subjects	%	MEHP		MEOHP		MEHHP
			OR	95% CI	OR	95% CI	OR	95% CI
Gestational age >41 weeks	7	2
Adjusted for creatinine			1.8*	1.1, 3.0	2.1**	1.2, 3.4	1.9*	1.1, 3.2
Adjusted for creatinine + covariatesb			2.0*	1.1, 3.5	2.2**	1.3, 4.0	2.1*	1.3, 3.7
Preterm delivery (<37 weeks)	14	5
Adjusted for creatinine			0.5*	0.3, 0.9	0.5*	0.2, 0.9	0.5*	0.3, 0.9
Adjusted for creatinine + covariatesc			0.5*	0.3, 0.9	0.4*	0.2, 0.9	0.5*	0.3, 0.9
Cesarean section delivery	62	22
Adjusted for creatinine			1.3	1.0, 1.6	1.4*	1.1, 1.9	1.4*	1.1, 1.8
Adjusted for creatinine + covariatesd			1.3*	1.0, 1.6	1.5**	1.1, 1.9	1.4*	1.1, 1.8
Failure to progress as reason for cesarean section delivery	18	6
Adjusted for creatinine			1.3	0.9, 1.8	1.6*	1.1, 2.4	1.5*	1.1, 2.2
Adjusted for creatinine + covariatese			1.2	0.9, 1.7	1.6*	1.1, 2.3	1.5*	1.0, 2.1

Abbreviations: CI, confidence interval; MEHHP, mono-2-ethylhexyl phthalate; MEHP, mono-2-ethylhexyl phthalate; MEOHP, mono-2-ethyl-5-oxohexyl phthalate; OR, odds ratio.

* P < 0.05; **P < 0.01.

^aChange in log odds per log-unit increase in urinary di-(2-ethylhexyl) phthalate metabolite concentration.

^bAdjusted for geographic site (Minnesota vs. California, Iowa, and Missouri) and respiratory conditions.

^cAdjusted for high blood pressure and nongestational diabetes.

^dAdjusted for mother's age (≥35 years vs. <35 years), geographic site (Minnesota vs. California, Iowa, and Missouri), nongestational diabetes, and fibroids.

^eAdjusted for parity, thyroid conditions, and high blood pressure. Information on the reason for cesarean section was missing for 2 subjects.