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. 2008 Dec 4;169(2):176–185. doi: 10.1093/aje/kwn300

Table 2.

Solvent Exposure and Risk of Non-Hodgkin Lymphoma by Average Exposure Intensity and Average Exposure Probability Among Connecticut Women, 1996–2000

Exposure Intensity
 Probability
No. of Controls No. of Cases ORa 95% CI No. of Controls No. of Cases ORa 95% CI
Any organic solvent
    Never 433 331 433 331
    Low 190 169 1.2 0.9, 1.5 156 131 1.1 0.8, 1.5
    Medium-high 93 101 1.4 1.0, 2.0 127 139 1.5 1.1, 1.9
    P for trend 0.01 <0.01
Benzene
    Never 589 481 589 481
    Low 94 80 1.0 0.7, 1.4 53 40 0.9 0.6, 1.4
    Medium-high 34 40 1.5 0.9, 2.4 75 80 1.3 0.9, 1.8
    P for trend 0.05 0.05
Formaldehyde
    Never 516 398 516 398
    Low 120 129 1.4 1.0, 1.8 166 165 1.3 1.0, 1.7
    Medium-high 81 74 1.2 0.8, 1.7 35 38 1.4 0.9, 2.3
    P for trend 0.21 0.11
Chlorinated solvents
    Never 530 405 530 405
    Low 108 107 1.3 0.9, 1.7 145 152 1.4 1.0, 1.8
    Medium-high 79 89 1.5 1.1, 2.1 42 44 1.5 0.9, 2.3
    P for trend 0.02 0.21
Chloroform
    Never 670 566 670 566
    Low 28 21 0.9 0.5, 1.7 14 8 0.8 0.3, 1.8
    Medium-high 19 14 0.9 0.4, 1.8 33 27 1.0 0.6, 1.7
    P for trend 0.75 0.94
Carbon tetrachloride
    Never 698 565 698 565
    Low 13 26 2.3 1.2, 4.5 19 36 2.3 1.3, 4.0
    Medium-high 6 10 2.2 0.8, 6.3 0 0
    P for trend 0.05 0.01
Dichloromethane
    Never 671 549 671 549
    Low 33 37 1.5 0.9, 2.4 41 48 1.6 1.0, 2.4
    Medium-high 13 15 1.6 0.7, 3.3 5 4 1.2 0.3, 4.4
    P for trend 0.11 0.34
Dichloroethane
    Never 659 543 659 543
    Low 55 57 1.3 0.9, 1.9 51 50 1.2 0.8, 1.9
    Medium-high 3 1 0.4 0.0, 4.2 7 8 1.5 0.5, 4.1
    P for trend 0.42 0.33
Methyl chloride
    Never 660 545 660 545
    Low 51 52 1.3 0.8, 1.9 49 49 1.2 0.8, 1.9
    Medium-high 6 4 1.0 0.3, 3.4 8 7 1.2 0.4, 3.4
    P for trend 0.68 0.26
Trichloroethylene
    Never 638 524 638 524
    Low 71 64 1.1 0.8, 1.6 48 43 1.1 0.7, 1.8
    Medium-high 8 13 2.2 0.9, 5.4 31 34 1.4 0.9, 2.4
    P for trend 0.06 0.37

Abbreviations: CI, confidence interval; OR, odds ratio.

a

Adjusted for age (continuous), family history of hematopoietic cancers (yes, no), alcohol consumption (yes, no), and race (white, black, other).