TABLE 3.
Population attributable risks for postmenopausal invasive breast cancer, Wisconsin, Massachusetts, and New Hampshire, 1997–2001
Risk factor | Summary PAR * |
Individual PAR |
||
PAR%† | 95% CI* | PAR%† | 95% CI | |
Factors not modifiable after menopause | 57.3 | 47.5, 65.4 | ||
Reproductive and menstrual factors | 42.2 | 30.7, 51.8 | ||
Age at menarche | 18.8 | 7.9, 29.0 | ||
Age at menopause | 13.7 | 6.6, 19.6 | ||
Age at first full-term pregnancy‡ | 5.2 | −3.2, 13.9 | ||
Parity | 13.3 | 6.9, 19.8 | ||
First-degree family history of breast cancer | 8.5 | 6.5, 10.5 | ||
Personal history of benign breast disease | 9.7 | 7.3, 12.0 | ||
Height at age 25 years | 11.0 | 3.5, 18.5 | ||
Factors modifiable after menopause | 40.7 | 23.0, 55.1 | ||
Current postmenopausal hormone use§ | 4.6 | −3.5, 11.9 | ||
Recent alcohol consumption (past year) | 6.1 | 2.1, 10.3 | ||
Weight gain since age 18 years¶ | 21.3 | 13.1, 29.3 | ||
Recent recreational physical activity# | 15.7 | −6.5, 33.7 |
PAR, population attributable risk; CI, confidence interval.
Assumes all participants move to the lowest risk category of factor or combination of factors, while other variables are held constant. For participants missing data for a variable, assumes no change in risk according to that variable. Adjusted for age, state of residence, weight at age 18 years, screening mammograms per year over the last 5 years, and all variables in tables 1 and 2.
Among parous women only.
Assumes no change in risk for never users.
Assumes no change in risk for women who lost more than 5 kg.
Averaged over the period 6 years to 1 year prior to the participant's reference date.