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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Dev Dyn. 2008 Dec;237(12):3681–3689. doi: 10.1002/dvdy.21770

Fig. 6.

Fig. 6

Expression patterns of the Wnt reporter TOPgal. A: TOPgal construct. B–E: Localization of Wnt signaling activity in the eyes of TOPgal embryos during early development. X-gal staining (blue) of coronal section through the optic vesicle at embryonic day (E) 9.25 (B), E9.5 (C), and E10.5 (E) and an E10.5 whole embryo (D) are shown. Black arrows in C–E indicate TOPgal activation restricted to the dorsal optic vesicle and retinal pigment epithelium (RPE). Arrowhead in E indicates no obvious TOPgal activation observed in the dorsal neural retina. *optic vesicle.