Table 1.
Different definitions used for DGF
| Number of studies | N (no. of patients) | References | |
|---|---|---|---|
| Dialysis-based definitions | |||
| Need for dialysis in the first week after transplant | 41 | 259 251 | [60–62,34,63,64,26,65,66,27,28,67, 32,68,2,33,22,69,70,43,40,71,4,13, 25,21,42,12,72,23,73,74,5,75,20, 76,24,37,77–80] |
| Need for dialysis in the first week after transplant once hyperacute rejection, vascular and urinary tract complications were ruled out | 2 | 760 | [56,38] |
| Need for dialysis after transplant | 2 | 737 | [79,29] |
| Need for dialysis in the first 10 days after transplant | 1 | 41 | [19] |
| Absence of life-sustaining renal function that requires dialysis on two or more occasions within the first week after transplant | 1 | 547 | [3] |
| Need for dialysis in the first 7 days after transplant with specific exclusion of single early post-operative dialysis performed for hyperkalemia | 1 | 319 | [81] |
| Return to maintenance hemodialysis within the first 4 days after transplantation | 1 | 263 | [18] |
| Creatinine-based definitions | |||
| Serum creatinine increased or remained unchanged or decreased <10%/day during 3 consecutive days after the transplant | 5 | 1471 | [9,45,39,82,35] |
| Creatinine reduction ratio <30% and /or urine creatinine on Day 2 <1000 mg | 2 | 401 | [31,83] |
| Serum creatinine >2.5 mg/dL on Day 7 or the need for post-transplant hemodialysis | 1 | 99 | [44] |
| Time required for the kidney to reach Crcl>10 mL/min greater than 1 week. | 1 | 843 | [11] |
| Failure of creatinine to decline in the first 48 h in the absence of rejection | 1 | 291 | [41] |
| Combination | |||
| Failure of serum creatinine to fall below pre-transplant levels, within 1 week regardless of the urine output | 1 | 158 | [36] |
| Patients with rise in serum Cr at 6–8 h post-operatively or <300 cc of urine despite adequate volume and diuretics | 1 | 143 | [30] |
| Dialysis requirement after transplant or a serum creatinine 150 μmol/L at Day 8 | 1 | 112 | [84] |
| Urine output <1 L in 24 h and <25% fall in serum creatinine from baseline in first 24 h post-transplant | 1 | 244 | [85] |
| Urine output <75 mL/h in first 48 h or failure of serum Cr to decrease by 10% in the first 48 h | 1 | 66 | [86] |
| Need for dialysis in the first week after transplant or failure of serum creatinine to decrease within 24 h after transplant | 1 | 104 | [80] |