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. 2009 Feb;13(1):43–61. doi: 10.1089/omi.2009.0011

FIG. 3.

FIG. 3.

Ratio of AUCs at two population edges (B/A) as a function of differences in population means when the toxicity threshold is positioned at the 10th, 5th, or the 1st percentile in the reference population A. Note the upward concavity and the nonlinear increase in the ratio of edge AUCs (population B/population A) (ordinate) with linear increments in the difference between population means (abscissa).