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. Author manuscript; available in PMC: 2009 Aug 14.
Published in final edited form as: Stroke. 2008 Apr 10;39(6):1869–1874. doi: 10.1161/STROKEAHA.107.506022

Figure 2.

Figure 2

A, Reduction of acute ischemic infarction in Ngb transgenic mice after focal cerebral ischemia. After 2 hours transient focal cerebral ischemia followed by 22 hours reperfusion, 2,3,5-triphenyltetrazolium hydrochloride infarction volume in the whole hemisphere and cortical regions was significantly reduced in Ngb-Tg mice compared with matching WT littermates. Mean±SEM, n=8 per group, *P<0.05. B, Reduction of late ischemic infarction in Ngb-Tg mouse brains. At 14 days after transient 1-hour focal cerebral ischemia, brain infarction was measured by hematoxylin & eosin staining and image analysis. The infarction was only located in subcortical regions, and the volume was significantly reduced in Ngb-Tg mice compared with WT mice. Mean±SEM, n=6 for Tg and 7 for WT per group, *P<0.05. All mice were 22 to 27 g males between 8 and 9 weeks old.