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. Author manuscript; available in PMC: 2009 Aug 14.
Published in final edited form as: Stroke. 2008 Apr 10;39(6):1869–1874. doi: 10.1161/STROKEAHA.107.506022

Table 1. Cerebral Blood Flow Measurements.

Measurements WT Ngb-Tg
Hydrogen clearance 83.3±3.2 88.5±8.9
Resting cerebral blood flow, mL/100 g/min
Laser Doppler flowmetry Ischemia Reperfusion Ischemia Reperfusion
Cerebral blood flow, % of preischemia baseline 17.5±1.5 96.5±3.9 14.8±2.3 96.2±4.7

Hydrogen clearance was used to measure resting cerebral blood flow; platinum wire was positioned under cortex caudate putamen nuclei. Laser Doppler flowmetry was used to measure cerebral blood flow during ischemia and reperfusion in Ngb-Tg and WT mice. Results are expressed as mean±SEM. N=5 per group for hydrogen clearance and n=10 per group for laser Doppler flowmetry measurement, respectively. All animals used were 23- to 27-g male mice. In both measurements, there were no statistically significant differences between WT and Ngb-Tg mice.