Table III.
Treatment | Age at evaluation | No. of animals | Testis wt (mg) | Body wt (g) |
---|---|---|---|---|
Controls (vehicle-treated) | 1–5 days | 3 | 5.5 ± 0.8 | 29.7 ± 1.0 |
Controls (non-treated) | 7 | 4.7 ± 0.4 | 29.0 ± 1.9 | |
Controls (combined) | 10 | 4.9 ± 0.6 | 29.2 ± 1.3 | |
MBP 500 mg/kg/day | 6 | 4.8 ± 0.6 | 29.3 ± 1.9 | |
Controls (vehicle-treated)a | 17–20 days | 5 | 11.5 ± 0.9 | 56.8 ± 4.1 |
MBP 500 mg/kg/daya | 5 | 11.0 ± 0.8 | 51.8 ± 3.8 | |
Controls (quantified)b | Adult | 5 | 522 ± 85 | 366 ± 15 |
Controls (not quantified)c | 12 | 516 ± 9 | 388 ± 17 | |
Controls (combined) | 17 | 518 ± 24 | 381 ± 13 | |
MBP 500 mg/kg/day | 5 | 605 ± 34 | 411 ± 21 |
aCo-twin males; bUntreated control adults most closely age-matched to MBP-exposed animals; cData from other untreated adults, showing that quantified adults are representative.