Table 3.
List of the imbalances found in the analysis of the Dysgerminoma.
Chr | Chromosome Band | Gain/Loss* | Position | Size (Mb) | Notes |
Chr 2 | 2p24.1 → 2q37.1 | enh | Chr2:24,134,000..233,241,000 | 209.10 | mosaic 30% |
Chr 2 | 2q37.1 → qtel | enh | Chr2:233,241,000..242,951,149 | 9.71 | More copies |
Chr 4 | 4q21.21 → qtel | dim | Chr4:80,599,000..191,273,063 | 110.70 | mosaic 30% |
Chr 8 | 8ptel → q24.13 | enh | Chr8:1..125,719,000 | 125.70 | |
Chr 8 | 8q24.13 → qtel | enh | Chr8:125,719,000..146,274,826 | 20.56 | mosaic 30% |
Chr 11 | 11p15.3 → 11q23.3 | dim | Chr11:11,570,000..119,487,000 | 107.90 | mosaic 30% |
Chr 11 | 11q23.3 → qtel | dim | Chr11:119,487,000..134,452,384 | 14.97 | |
Chr 12 | 12ptel → q23.1 | enh | Chr12:1..94,196,000 | 94.20 | More copies |
Chr 12 | 12q23.1 → qtel | enh | Chr12:94,196,000..132,349,534 | 38.15 | |
Chr 17 | 17q21.3 → qtel | enh | Chr17:38,922,000..78,774,742 | 39.85 | mosaic 30% |
Regions interested by the deletions/duplications/triplications are reported together with their mapping position and cytogenetic bands (hg 17/Build 35, May 2004), The size of each imbalance is always related to the platform resolution having 100 kb average distribution of the clones along the genome. The size of the intervening regions is shown, although it should be considered that breakpoints may fall within a segment of 100 kb (average) proximal and distal to the starting and ending clones. * Enh = enhanced log2 ratio (gain); dim = diminished log2 ratio (loss).