Table 1.
Nomenclature for the human and C. elegans genes discussed in this article
| Human | C. elegans | C. elegans protein | |
|---|---|---|---|
| SAC components | MAD1 | mdf-1 | MAD1MDF-1 |
| MAD2 | mdf-2 | MAD2MDF-2 | |
| MAD3 | san-1 | MAD3SAN-1 | |
| BUB1 | bub-1 | BUB-1 | |
| BUB3 | bub-3 | BUB-3 | |
| MPS1 | Not identified | - | |
| ZW10 | czw-1 | ZW10CZW-1 | |
| ROD | rod-1 | ROD-1 | |
| ZWILCH | zwl-1 | ZWILCHZWL-1 | |
| APC/C components | APC4 | emb-30 | APC4EMB-30 |
| APC8 | mat-3 | APC8MAT-3 | |
| CDC20 | fzy-1 | CDC20FZY-1 | |
| PI3K-AKT pathway | PI3K | age-1 | PI3KAGE-1 |
| AKT kinase | akt-1, akt-2 | AKT-1, AKT-2 | |
| PTEN | daf-18 | PTENDAF-18 | |
| CDK inhibitor | KIP | cki-1 | CKI-1 |