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. Author manuscript; available in PMC: 2009 Aug 15.
Published in final edited form as: Clin Exp Pharmacol Physiol. 2008 Oct 28;36(5-6):509–515. doi: 10.1111/j.1440-1681.2008.05107.x

Fig. 5.

Fig. 5

Intrarenal angiotensin (Ang) II protein levels in control and high IgA strain of ddY (HIGA) mice after harvest at 25 weeks of age. (a,b) Representative photomicrographs of immunoreactivity for AngII in control (a) and HIGA (b) mice. Immunoreactivity for AngII was noted mainly in some distal tubular cells in control mice and some proximal tubular cells were weakly positive for AngII. In HIGA mice, AngII staining increased significantly in proximal and distal tubular cells at 25 weeks of age. (c) Semiquantitative analysis of the intensity of intrarenal AngII immunoreactivity in control and HIGA mice at 25 weeks of age. Twenty tubulointerstitial lesions were examined for each mouse and the average intensity of AngII immunoreactivity for each mouse was used to calculate the ratio relative to control. Data are the mean±SEM. *P < 0.05 compared with control.