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. Author manuscript; available in PMC: 2010 Feb 15.
Published in final edited form as: Cancer Res. 2009 Aug 15;69(16):6405–6413. doi: 10.1158/0008-5472.CAN-09-1063

Figure 1. Overexpression of DEK in melanoma cell lines and tissue specimens.

Figure 1

A, immunoblotting of a panel of metastatic melanoma lines and primary foreskin-derived melanocytes (FM293 and FM298), with monoclonal (mAb) and polyclonal (polyAb) anti-DEK antibodies. B, Monoclonal anti-DEK band densities were quantified by densitometry, and relative DEK protein levels were normalized to FM293 melanocytes. The horizontal line indicates the mean for each group. C, SKY analysis showing increased copy number at chromosome 6 (yellow boxes) in SK-Mel-28, and SK-Mel-29, both expressing high levels of DEK (Fig. 1A and Fig. 2C). D, Representative examples of DEK staining in benign nevi (upper panels) and melanoma lesions (bottom panels) included in TMAs. The figures in the right column show higher magnification views of the indicated areas.

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