Figure 4. SST- and PV-expressing interneuron subgroups are generated contemporaneously during development.
The cortex of P30 mice, exposed to BrdU at E12.5, E14.5, or E16.5 as previously published (Xu et al., 2004), was processed for immunofluorescence for BrdU and either parvalbumin (A; PV) or somatostatin (B; SST) with arrows indicating co-expression. (C) The percentages of SST/PV co-labeling with BrdU are not significantly different at any of the ages studied in either the superficial (Layers II-IV) or deep (Layers V-VI) cortex.