TABLE III.

OR AND 95%CI FOR BREAST CANCER ASSOCIATED WITH QUARTILES OF TELOMERE LENGTH STRAFIED BY CO-VARIABLES, LONG ISLAND BREAST CANCER STUDY PROJECT, 1996–1997

Variable	Age-adjusted ORs (95%CIs) of Quartiles of Telomere Length				P for trend
	Q1 (longest)	Q2	Q3	Q4 (shortest)
Age (y)
< 50	1.00	1.18 (0.75–1.86)	1.66 (1.05–2.65)	1.78 (1.15–2.76) *	0.01
≥ 50	1.00	1.01 (0.75–1.34)	0.74 (0.56–1.00)	0.91 (0.68–1.22)	0.23
Menopausal status
Pre-menopausal	1.00	1.24 (0.80–1.91)	1.71 (1.10–2.67)	1.61 (1.05–2.45) ‡	0.01
Postmenopausal	1.00	1.05 (0.78–1.43)	0.72 (0.53–0.98)	0.92 (0.67–1.24)	0.19
Ever alcohol drinking
Nondrinkers	1.00	1.26 (0.85–1.89)	0.79 (0.52–1.19)	1.06 (0.71–1.57)	0.64
Drinkers	1.00	0.96 (0.70–1.30)	1.05 (0.76–1.43)	1.11 (0.82–1.50)	0.28
< 6.85 (gram/day)	1.00	0.91 (0.59–1.41)	1.02 (0.65–1.59)	1.08 (0.70–1.67)	0.52
≥ 6.85 (gram/day)	1.00	0.96 (0.62–1.48)	1.00 (0.64–1.57)	1.10 (0.72–1.67)	0.51
Active cigarette smoking status
Never	1.00	1.08 (0.75–1.55)	1.03 (0.71–1.49)	0.99 (0.70–1.42)	0.93
Former	1.00	0.99 (0.66–1.49)	0.82 (0.54–1.24)	1.28 (0.86–1.90)	0.28
Current	1.00	1.11 (0.63–1.94)	0.96 (0.54–1.72)	0.98 (0.56–1.73)	0.81
< 15 pack-years	1.00	1.19 (0.60–2.37)	0.93 (0.46–1.88)	1.37 (0.63–2.98)	0.63
≥ 15 pack-years	1.00	0.63 (0.33–1.24)	0.67 (0.32–1.24)	0.94 (0.48–1.82)	0.87
PAH-DNA adducts
Non detectable	1.00	1.90 (1.11–3.26)	1.28 (0.76–2.18)	1.92 (1.16–3.18)	0.05
Below median	1.00	1.04 (0.68–1.61)	0.87 (0.55–1.38)	1.33 (0.86–2.06)	0.31
Median and above	1.00	0.80 (0.53–1.20)	0.83 (0.53–1.30)	0.80 (0.51–1.25)	0.33
BMI (kg/m2)
< 25	1.00	0.85 (0.60–1.21)	0.83 (0.57–1.20)	0.94 (0.67–1.31)	0.87
≥25	1.00	1.31 (0.93–1.85)	1.08 (0.76–1.51)	1.27 (0.90–1.78)	0.33

^*P _interaction = 0.003, Likelihood ratio test P < 0.01

^†P _interaction = 0.004, Likelihood ratio test P < 0.01