TABLE IV.

OR AND 95%CI FOR BREAST CANCER ASSOCIATED WITH QUARTILES OF TELOMERE LENGTH STRAFIED BY OXIDATIVE DAMAGE BIOMARKERS, DIETARY AND/OR SUPPLEMENTAL ANTIOXIDANTS INTAKE^*, LONG ISLAND BREAST CANCER STUDY PROJECT, 1996–1997

Variable	Age-adjusted ORs (95%CIs) of Quartiles of Telomere Length				P for trend
	Q1 (longest)	Q2	Q3	Q4 (shortest)
15-F2t-IsoP (nmol/mmol creatinine)
< 0.71 (median)	1.00	1.10 (0.77–1.58)	1.10 (0.76–1.59	1.11 (0.78–1.59)	0.53
≥ 0.71 (median)	1.00	1.10 (0.78–1.55)	0.83 (0.59–1.18)	1.07 (0.76–1.49)	0.96
8-OxodG (nmol/mmol creatinine)
< 22.17 (median)	1.00	0.95 (0.67–1.36)	0.89 (0.62–1.28)	1.23 (0.88–1.73)	0.18
≥ 22.17 (median)	1.00	1.23 (0.87–1.74)	1.00 (0.70–1.42)	0.92 (0.65–1.31)	0.43
Any Fruits, Fruit Juices, and Vegetables †
0–34	1.00	1.27 (0.93–1.73)	1.06 (0.77–1.47)	1.16 (0.85–1.58)	0.39
≥ 35	1.00	0.81 (0.55–1.21)	0.83 (0.56–1.24)	0.99 (0.67–1.47)	0.99
Dietary + Supplemental β-carotene (mcg/d)
0–3817.2	1.00	1.33 (0.97–1.83)	1.10 (0.79–1.52)	1.48 (1.08–2.03) ‡	0.05
≥ 3817.3	1.00	0.82 (0.56–1.21)	0.75 (0.51–1.11)	0.81 (0.55–1.20)	0.25
Dietary + Supplemental Vitamin C (mg/d)
0–131.0	1.00	1.23 (0.88–1.70)	1.11 (0.80–1.53)	1.39 (1.01–1.92)	0.08
≥ 131.1	1.00	0.93 (0.64–1.35)	0.74 (0.49–1.10)	0.91 (0.62–1.34)	0.43
Dietary + Supplemental Vitamin E (a-te/d)
0–29.0	1.00	1.28 (0.92–1.77)	1.19 (0.86–1.65)	1.57 (1.14–2.18) §	0.01
≥ 29.1	1.00	0.88 (0.61–1.28)	0.67 (0.45–1.00)	0.78 (0.54–1.14)	0.11
Dietary α -carotene (mcg/d)
0–267.7	1.00	1.22 (0.89–1.68)	1.06 (0.76–1.46)	1.20 (0.88–1.64)	0.41
≥ 267.8	1.00	0.92 (0.63–1.36)	0.79 (0.53–1.18)	1.12 (0.75–1.66)	0.79

^*Variables were derived from a two-step process. Quintiles of the control distribution were used to form fifths. ORs of the last two-fifths and the first three-fifths were similar and therefore collapsed to form these binary variables

^†In ½ cup servings per week

^‡P _interaction = 0.035, Likelihood ratio test P < 0.05

^§P _interaction = 0.004, Likelihood ratio test P < 0.01