Incidence of non-fatal and fatal cardiovascular events in 10 years (events/100 person years) in controls, snorers, untreated mild to moderate OSA, untreated severe OSA, and OSA treated with CPAP in an observational study. All participants in this study were men. The healthy men were age and BMI matched to patients with OSA (healthy men had a mean age of 49.6 years and a mean BMI of 29.8 kg/m2 vs. men with untreated severe OSA who had a mean age of 49.9 years and a mean of BMI 30 kg/m2). Adherence with CPAP treatment was assessed with the timer built into each CPAP device. Patients with severe OSA had a mean CPAP use of ≥ 4 h/day. Data adapted from Marin et al. [40].
*p < 0.0001 versus healthy men
†p < 0.0012 versus healthy men