TABLE 1.
Study | Number of subjects | AHI ≥ 5 | AHI ≥ 15 | OSA syndrome | Methodology | Hypopnea Definition† |
---|---|---|---|---|---|---|
Wisconsin, U.S.A. ‡ 1993 [20] | Men: 352 Women: 250 (age 30–60) |
Men: 24% Women: 9% |
Men: 9% Women: 4% |
Men: 4% Women:2% |
Attended PSG (oronasal airflow and respiratory inductance plethysmography) | Discernable reduction in airflow plus ≥ 4% oxygen desaturation † |
Pennsylvania, U.S.A.¶ 1998, 2001 [22,23] | Men: 741 Women: 1000 (age 20–100) |
Men: 17% Women: 5% |
Men: 7% Women: 2% |
Men: 3.3% Women:1.2% |
Attended PSG (oronasal thermocouple) | Discernable reduction in airflow and ≥ 4% oxygen desaturation † |
Spain ¶ 2001 [21] | Men: 325 Women: 235 (age 30–70) |
Men: 26% Women:28% |
Men: 14% Women:7% |
Men: 3.4% Women:3% |
Attended PSG (oronasal thermister) | 50% airflow reduction Accompanied by either ≥ 4% oxygen desaturation or an EEG arousal |
Australia ‡ 1995 [24] | 294 men (age 40–65) | Men: 25.9% | Men: 10% (AHI ≥ 10) | Men: 3.1% Women: n/a |
MESAM IV portable monitoring (snoring and oximetry) | ≥ 3% oxygen desaturation along with increased heart rate of 10 beats/minute or burst of snoring † |
Hong Kong, China ‡ 2001, 2004 [25,26] | Men: 153 Women:106 (age 30–60) |
Men: 8.8% Women: 3.7% |
Men:5.3% Women: 1.2% |
Men: 4.1% Women:2.1% |
Attended PSG (oronasal thermister, thoracic and abdominal impedance belts) | Discernable reduction in airflow and ≥ 4% oxygen desaturation † |
Korea ‡ 2004 [27] | Men: 309 Women: 148 (age 40–69) |
Men: 27% Women: 16% |
Men: 10.1% Women: 4.7% |
Men: 4.5% Women:3.2% |
In laboratory or home PSG (oronasal thermister) | Discernable reduction in airflow and ≥ oxygen 4% desaturation † |
India ‡ 2004 [28] | 250 men (age 35–65) | Men: 19.5% | Men: 8.4% | Men: 7.5% Women: n/a |
Home PSG (oronasal thermister) | Discernable 50% reduction in airflow and ≥ 4% oxygen desaturation † |
India ‡ 2006 [29] | Men: 88 Women: 63 (age 30–60) |
Men: 19.7% Women: 7.4% |
n/a | Men: 4.9% Women:2.1% |
Attended in laboratory PSG | Discernable 50% reduction in airflow and ≥ 4% oxygen desaturation † |
Studies that did not use EEG microarousal as part of the definition of hypopnea
OSA Syndrome defined as: AHI ≥ 5 + EDS
OSA Syndrome defined as: AHI ≥ 10 + EDS
MESAM IV: Madaus Medizin-Elektronik – Freiburg, Germany; PSG: Polysomnography